Is everyone who develops TRO affected in the same way?

• No

• wide variation

  • mild irritation and lid retraction that resolve totally
  • severe orbital infiltration with visual loss

• More severe disease

  • older patients (average age of 52 vs. 36 for milder disease)
  • less of a gender difference (female-to-male ratio of 1.5:1 in severe disease vs. 8.6:1 in mild disease)

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